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Multipleendocrineadenomatype1(MEN-1)

Multipleendocrineneoplasiatype1(MEN-1)isaninheritedsyndromecharacterizedbyhyperplasia,orsometimesadenoma,pancreaticisletcelltumor(alsocalledpancreaticneuroendocrinetumor),and/orpituitarytumor.Duodenalgastricjuicetumors,benigntumorsofthejejunum,benigntumorsoftheadrenalglands,andlipomasmayalsoexist.Commonclinicalmanifestationsincludehyperthyroidismandasymptomatichypercalcemia.Geneticscreeningcanbeusedtodetectdiseasedgenecarriers.Diagnosisreliesonhormonetestingandimaging.Diagnosisreliesonhormonedeterminationandimagingtests.Whenpossible,surgerytoremovethetumor.

译文

多发性内分泌腺瘤病1型（MEN-1）

多发性内分泌腺瘤病1型（MEN-1）是一遗传性综合征，特点为增生，或有时是腺瘤、胰岛细胞瘤(也称为胰腺神经内分泌肿瘤)，和/或垂体肿瘤。十二指肠促胃液瘤、空肠的良性肿瘤、肾上腺的良性肿瘤以及脂肪瘤也可能存在。常见临床表现包括甲状腺功能亢进和无症状性高血钙症。基因筛查可用于检出病变基因携带者。诊断依靠激素测定及影像学检查。诊断依靠激素测定及影像学检查。可能时,手术切除肿瘤。

MEDICAL

ENGLISH

重点词汇

endocrine

/?end?kr?n/内分泌（腺）的adj.

neoplasia

/?nio??ple???/肿瘤形成n.

hyperplasia

/?ha?p?r?ple???/增生，畸形生长n.

adenoma

/??d??no?m?/腺瘤n.

pancreatic

/?p??kri??t?k/胰腺的adj.

islet

/?a?l?t/胰岛n.

neuroendocrine

/?n?ro??endo??kr?n/神经内分泌的adj.

pituitary

/p??tu??teri/（脑）垂体n.

duodenal

/?du???di?nl/十二指肠的adj.

benign

/b??na?n/良性的adj.

jejunum

/d???d?u?n?m/空肠n.

lipoma

/l??po?m?/脂肪瘤n.

hyperthyroidism

/?ha?p?r?θa?r??d?z?m/甲状腺功能亢进n.

asymptomatic

/?e?s?mpt??m?t?k/无症状的adj.

hypercalcemia

/,haip?,k?lsi:mi?/血钙过多，高血钙症n.

geneticscreening

基因筛查，遗传筛查

genecarrier

基因携带者

-TheEnd-

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